Amaia Cipitria

This study shows that PEA-coated monetites functionalized with fibronectin and low-dose rhBMP-2 promote structurally mature bone regeneration in critical-sized defects.

This study shows that matrix stiffness influences breast cancer cell dormancy states, with soft matrices inducing transient dormancy and stiff matrices causing prolonged dormancy.

This study develops a tunable 3D lung-mimicking model to investigate how ECM mechanics influence tumor growth and genomic instability in breast cancer metastasis.

This paper develops 3D patterned alginate-collagen hydrogels that spatially guide endothelial cell invasion and proliferation by controlling collagen fibrillogenesis, degradation, and viscoelasticity.

This study correlates in vivo MRE-derived mechanical properties with ex vivo tissue mechanics and histopathology in PDAC, showing that softer surrounding environments are linked to stiffer tumors and poorer prognosis.

This study shows breast cancer cell-derived extracellular vesicles actively accelerate collagen fibrillogenesis and integrate into the matrix, influencing ECM remodeling.

This paper presents a theoretical model showing how tumor microenvironment feedback can lead to dynamic cancer dormancy and awakening through changing cancer-host interactions.

This study shows that the stiffness and viscoelasticity of adipose tissue-derived hydrogels affect breast cancer cell proliferation, growth, migration, and invasion.

This paper shows that anisotropic hydrogel degradation patterns enhance hMSC alignment, mechanotransduction, and osteogenic differentiation compared to uniform materials.

This study investigates how extracellular vesicle mobility in collagen I hydrogels is influenced by RGD-binding integrins, showing that integrin inhibition increases EV mobility.

This paper introduces a 3D stochastic cellular automaton model to simulate bone remodeling dynamics and derives a phase diagram showing how parameter changes affect the process.

This study shows aging impairs muscle regeneration by promoting fibro/fatty degeneration and inhibiting inflammation resolution through reduced Periostin in fibro/adipogenic progenitors.