GeneticsProceedings of the National Academy of SciencesPeer-reviewed
Leveraging a natural murine meiotic drive to suppress invasive populations
Luke Gierus, Ayşegül C. Birand, Mark D. Bunting…·Paul Quinton Thomas
This paper proposes a gene drive strategy called tCRISPR to suppress invasive mouse populations by leveraging the t haplotype's biased transmission and inactivating mutations in a female fertility gene.
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