Author

Manuel Micheloni

Istituto Nazionale di Fisica NucleareORCID 0000-0002-9938-5232Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Approach:mechanistic / dynamical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Lorenzo PetrolliiD· 2 shared Raffaello PotestioiD· 2 shared Luca TubianaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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2 shared papersBiophysics

Lorenzo PetrolliORCID

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2 papers

Recent·Most cited

BiophysicsPhysics in Medicine and BiologyPeer-reviewedMar 19, 2026

Dynamical insights on the role of supercoiling on DNA radiosensitivity

Manuel Micheloni, Raffaello Potestio, Lorenzo Petrolli

The paper uses molecular dynamics simulations to study how supercoiling affects DNA radiosensitivity, finding that negative supercoiling increases rupture likelihood under specific conditions.

DOI 10.1088/1361-6560/ae54fc

DNA methylationmechanistic / dynamical model

𝕏 PostBluesky

BiophysicsBiophysical ReportsPeer-reviewedOct 31, 2025

Sequence and supercoiling-dependent effects on the structural dynamics of DNA minicircles

Manuel Micheloni, Luca Tubiana, Raffaello Potestio, Lorenzo Petrolli

The paper uses molecular dynamics simulations to study how DNA sequence and superhelical density affect structural dynamics in minicircles, finding that undercoiling leads to stable denaturation bubbles.

2 citations

DNA methylationstructural biology

𝕏 PostBluesky