BiophysicsGenome biologyPeer-reviewed
Cohesin distribution alone predicts chromatin organization in yeast via conserved-current loop extrusion.
Tianyu Yuan, Hao Yan, Kevin Li…·S. G. J. Mochrie
The paper introduces the CCLE model to predict chromatin organization in yeast using cohesin ChIP-seq data, showing it accurately predicts TADs without relying on CTCF.