Michael D. Cusimano

The paper identifies a gene co-expression module that accurately predicts meningioma recurrence with an AUC of 0.81.

The paper identifies shared immune cell composition and transcriptome responses across sepsis and trauma in critical illness, revealing subgroups associated with clinical outcomes.

The paper analyzes bulk transcriptomics data from meningiomas to show that skull base meningiomas have a distinct immune landscape compared to convexity meningiomas.

The paper identifies two subgroups of atypical meningiomas using oncogenic signatures, reclassifying 72% of cases as either benign grade 1-like or malignant grade 3-like based on recurrence rates and biological processes.

This study identifies multimorbidity subgroups in critical care patients and finds one subgroup has over 2-fold higher sepsis-related mortality.