Alexander Arthur Wurm

This study develops an ex vivo drug sensitivity testing platform for rare solid tumors and finds that high in vitro sensitivity correlates with clinical benefit and progression-free survival.

This study evaluates the efficacy of CD38 and CD20 IgG1/IgA2 antibodies in mediating myeloid cell-mediated killing of B-ALL, showing enhanced activity with CD47/SIRPα blockade.

This study shows that mesenchymal-epithelial transition (MET) in breast cancer cells reduces proliferation but enhances immune evasion, suggesting MET promotes tumor outgrowth through immune survival rather than proliferation.

This study identifies KAT2A as a therapeutic target in a subset of well-differentiated, microsatellite-stable colorectal cancers by showing its dependency and functional consequences.