Author

Michael R. Speicher

Medical University of GrazORCID 0000-0003-0105-955XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:whole-genome sequencing· 3 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Isaac LazzeriiD· 2 shared Martin KircheriD· 2 shared Albert WölfleriD· 1 shared Armin GergeriD· 1 shared Armin ZebischiD· 1 shared Benjamin SpiegliD· 1 shared Brandon White· 1 shared Charles E.S. Roberts· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBioinformatics

Isaac LazzeriORCID

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3 papers

Recent·Most cited

BioinformaticsComputational and Structural Biotechnology JournalPeer-reviewedAug 11, 2024

LBFextract: unveiling transcription factor dynamics from liquid biopsy data

Isaac Lazzeri, Benjamin Spiegl, Samantha Ourania Hasenleithner…·Martin Kircher

LBFextract extracts transcription factor dynamics from liquid biopsy data to improve reproducibility and subtype classification in prostate cancer.

7 citations

humanDNA methylation

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Genetic & Genomic MedicineGigaSciencePeer-reviewedJan 1, 2024

cfDNA UniFlow: A unified preprocessing pipeline for cell-free DNA data from liquid biopsies

Sebastian Röner, Lea Burkard, Michael R. Speicher, Martin Kircher

The paper introduces cfDNA UniFlow, a unified preprocessing pipeline for cell-free DNA data, enabling standardized processing and analysis across different settings.

4 citations

whole-genome sequencingstatistical model

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Cancer BiologybioRxivPreprintMar 31, 2019

Inference of tumor cell-specific transcription factor binding from cell-free DNA enables tumor subtype prediction and early detection of cancer

Peter Ulz, Samantha Perakis, Qing Zhou…·Michael R. Speicher

This study infers tumor cell-specific transcription factor binding from cell-free DNA to predict tumor subtypes and detect cancer early.

DOI 10.1101/456681

humanDNA methylation

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