Systemic Lupus Erythematosus Serum Stimulation of Human Intestinal Organoids Induces Changes in Goblet Cell Differentiation and Mitochondrial Fitness
Inga Viktoria Hensel, Szabolcs Éliás, Michelle Steinhauer…·Martín Resnik-Docampo
This study shows that SLE serum affects intestinal organoids by altering mucus, mitochondrial fitness, and gene expression, linking gut barrier dysfunction to autoimmune disease.