Haoqing Wang

Gold-nanorod surface-enhanced Raman spectroscopy with LightGBM separates CAR T from untransduced T cells, tracks antigen-specific activation dynamics, and discriminates sorted CAR+ from CAR- patient T cells.

The paper shows that Rhi recruitment to genomic targets in Drosophila is mediated by a combination of H3K9me3 binding and a piRNA-guided scaffold involving Panx and Kipf.

The paper shows that AP-7-168 induces β2AR dimerization by acting as a molecular glue, revealing a new allosteric mechanism for GPCR modulation.

This study investigates the Zdhhc5-GOLGA7 protein complex involved in non-apoptotic cancer cell death induced by CIL56, revealing key residues critical for complex formation and cell death.

This study identifies structural features determining G protein coupling specificity at a class A GPCR using a Gi-biased agonist.

This paper identifies a negative allosteric modulator of the μ-opioid receptor that blocks agonist activity and enhances naloxone efficacy, offering potential for safer opioid overdose reversal.

The paper proposes a step-wise activation model for metabotropic glutamate receptor subtype 5, supported by structural and fluorescence imaging data of different activation states.