Author
University of LeedsORCID 0000-0003-0280-4005Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
4 papers
Recent·Most cited
James Shelford, Selena G. Burgess, Elena V. Rostkova…·Stephen Royle
This study determines the structure of the ch-TOG-TACC3 interaction and shows that inhibiting it causes pericentriolar material fragmentation and delayed mitosis.
Oliver J. Debski-Antoniak, Alex J. Flynn, David Paul Klebl…·Juan Fontana
This paper isolates and characterizes Affimers, antibody-like proteins, that inhibit influenza A virus H3 subtype infection in vitro and block HA-receptor interactions.
Katarzyna Z. Haza, Heather L. Martin, Ajinkya Rao…·Darren Charles Tomlinson
This paper identifies two RAS-binding Affimer proteins that inhibit RAS function and reveal a novel druggable SII/3 pocket.
Jennifer A. Miles, Fruzsina Hobor, James Taylor…·Thomas A. Edwards
The paper identifies Affimer reagents that selectively bind BCL-2 family proteins through non-canonical structural motifs, showing competitive inhibition and conformational changes.