Lilliana Radoshevich

The paper constructs a spatiotemporal atlas of the androgen receptor proximal interactome using PL-qMS, identifying 4,751 AR-PIPs and revealing a retromer-AR-TMF1 axis involved in androgen-regulated transcription.

The paper identifies two modes of nuclear receptor engagement through LXXLL motifs, showing how AR-V7 loses LXXLL-enriched interactions in cancer.

This study shows TRIM21 acts as a molecular rheostat regulating influenza A virus replication by modulating ubiquitination and innate immune signaling, with PRKDC as a compensatory antiviral factor when TRIM21 is absent.

This study identifies ISG15 as a key host defense mechanism against Salmonella typhoid toxin, showing it promotes cell survival and reduces bacterial burden through a STING-dependent pathway.

This study shows that enhanced ISGylation reduces respiratory distress in Francisella novicida infection by modulating SAMHD1 function, suggesting USP18 inhibition as a therapeutic strategy.

The paper identifies differences in the tau interactome between fetal and Alzheimer disease brains, showing isoform-dependent interactions with 14-3-3 proteins.