Panagiota Klentrou

This study shows that inducing oxidative stress in pancreatic cancer cells creates an effective whole-cell vaccine that enhances anti-tumor immunity and synergizes with PD-1 blockade.

This study identifies isoDGR-induced endothelial cytoskeletal disruption as a key driver of age-related BBB breakdown and shows that targeting isoDGR preserves BBB integrity and reduces neuroinflammation.

This study shows that an anti-isoDGR antibody reduces atherosclerosis and metabolic dysfunction in ApoE-/- mice fed a Western diet.

This study identifies isoDGR-damaged proteins as contributors to age-related lung pathology and shows that anti-isoDGR antibodies reduce lung damage in mice.