Author

Xinxin Si

Jiangsu Ocean UniversityORCID 0000-0003-0393-4223Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:deep learning· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Jie XiaiD· 2 shared Song WuiD· 2 shared Chenliang QianiD· 1 shared Dongmei WangiD· 1 shared Gao Zhang· 1 shared Hao WangiD· 1 shared Hongwei JiniD· 1 shared Jiale GuoiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersPharmacology & Toxicology

Jie XiaORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologyInternational Journal of Biological MacromoleculesPeer-reviewedMay 2, 2024

Discovery of a Novel Chemotype as DYRK1A Inhibitors against Alzheimer's disease: Computational Modeling and Biological Evaluation

Nianzhuang Qiu, Chenliang Qian, Tingting Guo…·Jie Xia

This paper identifies a novel DYRK1A inhibitor, compound Q17, through computational screening and validates its efficacy in reducing AD-related pathology in vitro and in vivo.

8 citations

mouseproteomics

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BioinformaticsJournal of Chemical Information and ModelingPeer-reviewedJan 24, 2024

AutoMolDesigner for Antibiotic Discovery: An AI-based Open-source Software for Automated Design of Small-molecule Antibiotics

Tao Shen, Jiale Guo, Zunsheng Han…·Jie Xia

AutoMolDesigner is an open-source AI tool for automated small-molecule antibiotic design, combining generative deep learning and automated machine learning for efficient antibiotic discovery.

23 citationstop 4%

machine learning (classical)drug response / drug discovery

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