Timothy M Walker

This study finds higher QuantiFERON-TB Gold Plus IFNγ concentrations are associated with progression to symptomatic TB and meet WHO biomarker thresholds.

This study compares long-read and short-read sequencing for tuberculosis drug resistance and outbreak analysis, finding they are comparable with minimal differences in key clinical outputs.

This paper develops an automated method to build a comprehensive catalogue of resistance-associated variants for M. tuberculosis, achieving comparable performance to existing catalogues without expert rules.

GenomegaMap estimates genome-wide dN/dS ratios across 10,209 tuberculosis genomes to identify selection pressures shaping the pathogen's evolution.

This paper predicts pyrazinamide resistance in Mycobacterium tuberculosis using machine learning models trained on pncA mutations and structural features, achieving 80.2% sensitivity and 76.9% specificity.

This paper develops a tool to predict antibiotic resistance in S. aureus and M. tuberculosis from genome sequences with high accuracy and speed.