Caj H. Haglund

This study identifies a stereotypic organization of pancreatic ductal adenocarcinoma cells based on WNT signaling and Notch ligand interactions, showing that disrupting this equilibrium suppresses tumor growth and metastasis.

This study characterizes and spatially annotates normal and cancer-associated colon fibroblasts using single-cell RNA-sequencing and spatial transcriptomics.

This study identifies HOXB6 and HOXB8 as regulators of immune-cancer cell interactions in pancreatic cancer, showing their role in promoting tumorigenesis and treatment resistance.

This study identifies E2F1 and E2F8 as key regulators promoting cell proliferation, survival, and migration in pancreatic ductal adenocarcinoma.