Isabella Artner

This study identifies HOXB6 and HOXB8 as regulators of immune-cancer cell interactions in pancreatic cancer, showing their role in promoting tumorigenesis and treatment resistance.

This study identifies E2F1 and E2F8 as key regulators promoting cell proliferation, survival, and migration in pancreatic ductal adenocarcinoma.

This study identifies Hamlet as a key regulator of epithelial tissue fusion in Drosophila reproductive system, revealing its role in gene regulation and tissue connectivity.

This study shows that TYK2 is critical for β-cell development by regulating KRAS and IFN responses, suggesting TYK2 inhibition as a therapeutic target for type 1 diabetes.

The paper introduces Islet Gene View (IGW), a platform that integrates gene expression and phenotypic data from pancreatic islets to explore T2D-related gene expression changes and their functional implications.

The paper shows that a loss-of-function variant in ZnT8 improves insulin secretion and protects against type 2 diabetes by enhancing glucose responsiveness and proinsulin conversion.