Author

Frédérique Souazé

Centre National de la Recherche ScientifiqueORCID 0000-0003-0476-2603Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Chloé C. LefebvreiD· 2 shared Mario CamponeiD· 2 shared Philippe Paul JuiniD· 2 shared David ChironiD· 1 shared Elise Douillard· 1 shared François GuillonneauiD· 1 shared Isabelle CorreiD· 1 shared Jennifer DerrieniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Chloé C. LefebvreORCID

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2 papers

Recent·Most cited

Cancer BiologyCell Death and DiseasePeer-reviewedAug 9, 2025

MCL-1 as a molecular switch between myofibroblastic and pro-angiogenic features of breast cancer-associated fibroblasts

Chloé C. Lefebvre, Philippine Giowachini, Jennifer Derrien…·Frédérique Souazé

This study shows that MCL-1 regulates the switch between myofibroblastic and pro-angiogenic features in breast cancer-associated fibroblasts, with implications for treatment response.

4 citations

humanbulk RNA-seq

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Cancer BiologyScientific ReportsPeer-reviewedJun 19, 2024

Cancer associated fibroblasts mitigate the efficacy of the combination treatment of chemotherapy and BCL-xL targeting in triple negative breast cancer cells

Lisa Nocquet, Julie Roul, Chloé C. Lefebvre…·Frédérique Souazé

This study shows that BCL-xL promotes chemotherapy resistance in TNBC cells, and CAFs reduce the effectiveness of chemotherapy combined with BCL-xL inhibition.

26 citations

humanbulk RNA-seq

𝕏 PostBluesky