Author

Daria N. Shalaeva

ORCID 0000-0003-0582-2612Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:chromatin & epigenetic regulation· 2 Assay:structural biology· 2 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Approach:statistical model· 1

Frequent Co-Authors

Dmitry A. CherepanoviD· 2 shared Armen Y. MulkidjanianiD· 1 shared Armen Y. Mulkidjanian· 1 shared Gert VriendiD· 1 shared Michael Y. GalperiniD· 1 shared Michael Y. Galperin· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 9 mutual co-author links

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2 shared papersBiophysics

Dmitry A. CherepanovORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintMar 23, 2019

Class A GPCRs use the membrane potential to increase their sensitivity and selectivity

Daria N. Shalaeva, Dmitry A. Cherepanov, Michael Y. Galperin…·Armen Y. Mulkidjanian

This study shows that class A GPCRs use the membrane potential to enhance their sensitivity and selectivity by coupling sodium ion translocation to receptor activation.

DOI 10.1101/587576

humanstructural biology

𝕏 PostBluesky

Evolutionary BiologybioRxivPreprintOct 11, 2018

Comparative analysis of active sites in P-loop nucleoside triphosphatases suggests an ancestral activation mechanism

Daria N. Shalaeva, Dmitry A. Cherepanov, Michael Y. Galperin, Armen Y. Mulkidjanian

The paper compares active sites in P-loop NTPases and uses MD simulations to suggest a common ancestral activation mechanism involving gamma-phosphate rotation.

DOI 10.1101/439992

structural biologymechanistic / dynamical model

𝕏 PostBluesky