ImmunologybioRxivPreprint
Aryl Hydrocarbon Receptor Suppresses Eosinophilic Esophagitis Responses through OVOL1 and SPINK7
Nurit P. Azouz, Andrea M. Klingler, Mark Rochman…·Marc E. Rothenberg
This study identifies OVOL1 as a regulator of SPINK7 expression in eosinophilic esophagitis, showing AHR activation enhances SPINK7 and barrier function while IL-4 and IL-13 inhibit this pathway.
DOI 10.1101/2023.05.17.541192