Author
University of PittsburghORCID 0000-0003-0764-9585Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Aidan R. Cole, Raquel Buj, Apoorva Uboveja…·Katherine M. Aird
This study shows that chemotherapy-induced senescence-associated secretome promotes metastasis in ovarian cancer by reprogramming metabolism and increasing cell detachment.
Amal Taher Elhaw, Priscilla W. Tang, Ya-Yun Cheng…·Nadine Hempel
This study identifies RHOV as a detachment-sensitive Rho GTPase critical for ovarian cancer peritoneal metastasis by enhancing anoikis resistance and cytoskeletal remodeling.
Ya-Yun Cheng, Beth L. Worley, Zaineb Javed…·Nadine Hempel
This study shows that loss of MPZL3 promotes EMT and chemoresistance in ovarian cancer by reducing adhesion and increasing drug resistance.
Zaineb Javed, Dong Hui Shin, Weihua Pan…·Nadine Hempel
This study identifies an alternative splice variant of Drp1 in ovarian cancer that promotes metastasis and chemoresistance by altering mitochondrial dynamics.
Caroline A. Chang, Ya-Yun Cheng, Shriya Kamlapurkar…·Nadine Hempel
This study shows GPX3 is necessary for ovarian cancer growth in vivo and promotes GDF15 expression, linking it to immune checkpoint inhibitor response.