Author

Haifeng Qian

Hangzhou Institute of Medicine, Chinese Academy of SciencesORCID 0000-0003-0807-9991Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Ailan Lin· 1 shared Chulin ShaiD· 1 shared Guoyan LuoiD· 1 shared Hong WangiD· 1 shared Jingjing Qin· 1 shared Kedan GuiD· 1 shared Mengyang FaniD· 1 shared Qin WuiD· 1 shared

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2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Ailan Lin

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1 paper

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedAug 8, 2024

Blocker-SELEX: A Structure-guided Strategy for Developing Inhibitory Aptamers Disrupting Undruggable Transcription Factor Interactions

Tongqing Li, Xueying Liu, Haifeng Qian…·Weihong Tan

This paper introduces Blocker-SELEX, a structure-guided method to design inhibitory aptamers that disrupt transcription factor interactions, demonstrating efficacy against SCAF4/SCAF8-RNAP2 and WDR5-MYC complexes.

37 citationstop 4%

deep learningexperimental assay

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