David S. Weiss

The paper identifies sigmaE as a key regulator of colistin heteroresistance in Enterobacter cloacae, showing that multiple regulatory systems are required for this resistance.

This study identifies bacterial genera using 3D surface topography features with 97% accuracy, showing taxonomic information persists at the population morphology level.

The paper shows that a shift in pre-existing antibiotic heteroresistance, not de novo mutation, explains a change from susceptible to resistant classification during treatment.

This study identifies antibiotic heteroresistance in eight Lactobacillus species, highlighting potential clinical implications for probiotics and commensals.

The paper shows that glucose availability increases fosfomycin resistance in Enterobacter cloacae by altering GlpT expression and enhancing fosA gene activity.

The paper tests sulbactam-durlobactam susceptibility in cefiderocol heteroresistant Acinetobacter isolates and finds no heteroresistance, supporting its efficacy and potential prioritization over cefiderocol.

This study identifies two glycosyltransferases involved in synthesizing glycolipids in C. difficile and highlights their role in bacterial physiology.

This paper develops two mathematical models of heteroresistance to explore how resistance ascends and reverts during antibiotic treatment, showing that current identification methods are insufficient.

This study shows that gut commensal bacteria can translocate to the brain in mice with dysbiosis and neurological disease, correlating with neuroinflammation and protein aggregation.

The paper shows that pre-existing phenotypic heterogeneity can lead to heteroresistance upon gene acquisition, highlighting a mechanism for antibiotic resistance evolution.