Li Ma

The paper identifies a GLRX2 mutation causing mitochondrial dysfunction and somersaulting behavior in Darwin's pigeons, showing how domestication can expose deleterious variants.

The paper presents CattleGTEx, a resource characterizing regulatory effects in cattle, resolving GWAS signals and providing insights into adaptive evolution and selection.

This study constructs a multi-tissue cell atlas of pigs, identifies cell-type-specific gene regulation, and links these to complex traits and human phenotypes.

The paper describes a new salamander species, Pachytriton, from Anhui, China, based on morphological and molecular analyses.

The paper constructs a bovine epigenomic atlas to annotate regulatory elements and decode the regulatory syntax of the cattle genome, aiding in fine-mapping GWAS loci for complex traits.

GSOR and MTAO detect widespread cis-regulatory effects on bovine complex traits by linking gene expression with genetic scores and multi-trait associations.

The paper constructs a cattle cell-type-specific regulatory variant atlas by integrating bulk and single-cell RNA-seq data, identifying eQTL and linking them to GWAS loci for breeding insights.

The paper performs a multi-breed meta-GWAS in pigs to identify genomic regions associated with complex traits and integrates with PigGTEx to prioritize variant-gene-tissue-trait circuits.

scRecover imputes dropout zeros in scRNA-seq data while preserving true zeros, improving downstream analysis through accurate zero discrimination.

This study identifies O-GlcNAcylation of YTHDF2 at Thr-49 as a regulator of ERK-dependent phosphorylation and tumor growth in lung carcinoma.

The paper presents PigGTEx, a resource linking genetic variants to transcriptomic phenotypes in pigs, showing pigs' similarity to humans in gene regulation and complex traits.

The paper constructs a cattle Genotype-Tissue Expression atlas and identifies genetic regulatory variants linked to gene expression and traits in cattle.

The paper constructs an ACE2 expression atlas across mammals to identify potential hosts and transmission pathways for SARS-CoV-2.

The paper performs GWAS and fine-mapping on seven health traits in Holstein cattle to identify genetic variants and candidate genes associated with health outcomes.

The paper imputes sequence variants in Holstein bulls and performs fine-mapping of 35 traits using a Bayesian approach, identifying candidate genes and variants.