Sylvain Delaunay

This study shows that SRSF2 mutations cause DNA damage and cell cycle arrest, highlighting its role in transcription regulation during cell division.

The paper identifies essential RNA modifications in cancer using CRISPR screens and finds that mitochondrial metabolic plasticity influences drug resistance through specific RNA modifications.

This study identifies a tumor-suppressive strategy in naked mole-rats that couples regenerative cell turnover with a tumor-hostile stromal niche to prevent cancer.