Author

Christopher T. Lohans

Queen's UniversityORCID 0000-0003-1094-0349Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Assay:proteomics· 1

Frequent Co-Authors

Mitchell A JeffsiD· 3 shared Josephine L Liu· 2 shared Prameet M. ShethiD· 2 shared Rachel A. V. Gray· 2 shared Montserrat Mora-OchomogoiD· 1 shared Shreyas Bhat· 1 shared Xena X. LiiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 17 mutual co-author links

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3 shared papersMicrobiology

Mitchell A JeffsORCID

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3 papers

Recent·Most cited

MicrobiologyACS Infectious DiseasesPeer-reviewedAug 8, 2025

Rapid Detection of Carbapenemase-Producing Organisms Using a Luminescent Biosensor

Mitchell A Jeffs, Shreyas Bhat, Josephine L Liu…·Christopher T. Lohans

This paper introduces a luminescent biosensor for rapid detection of carbapenemase-producing organisms with 100% sensitivity and specificity.

1 citation

experimental assayhost-pathogen & immune response

𝕏 PostBluesky

MicrobiologyRSC Chemical BiologyPeer-reviewedJan 1, 2025

Contributions of β-lactamase substrate specificity and outer membrane permeability to the antibiotic sheltering of β-lactam-susceptible bacteria

Montserrat Mora-Ochomogo, Mitchell A Jeffs, Josephine L Liu, Christopher T. Lohans

This study develops a luminescence assay to quantify antibiotic sheltering in mixed microbial populations and identifies factors influencing this phenomenon.

5 citations

experimental assayhost-pathogen & immune response

𝕏 PostBluesky

MicrobiologyChemical CommunicationsPeer-reviewedJan 1, 2023

Development of a Whole-Cell Biosensor for β-Lactamase Inhibitor Discovery

Mitchell A Jeffs, Rachel A. V. Gray, Prameet M. Sheth, Christopher T. Lohans

This paper develops a whole-cell E. coli biosensor to quantify β-lactamase inhibition in a cellular context and evaluates existing inhibitors.

8 citations

E. coliproteomics

𝕏 PostBluesky