Jelle Matthijnssens

This paper develops optimized RNA polymerase II-driven minigenomes for Nipah virus to enable safer research and antiviral screening.

The paper analyzes microbial diversity in Aedes aegypti mosquitoes across life stages and breeding sites, finding convergent enrichment of Gammaproteobacteria, suggesting maternal transmission.

This study identifies distinct viral communities in HS patients compared to controls, highlighting differences in phage composition and potential roles in disease progression.

This study evaluates combinations of approved oral nucleoside analogues against multiple alphaviruses in vitro and in vivo, finding synergistic antiviral effects and reduced viral mutation rates with combination therapy.

The paper investigates viruses in Cameroonian blackflies, finding a high abundance of novel viral sequences but no known neurotropic viruses, suggesting potential zoonotic disease risks.

This study shows that fecal microbial load, not disease, is the main driver of gut microbiome changes and identifies it as a major confounder in microbiome studies.

This study shows ToBRFV is widely detected in environmental samples, highlighting the need for contextual information to interpret test results accurately.

The study profiles the virome of Culex and Aedes mosquitoes in Belgium, finding no abundant core virome and identifying 45 viruses, 28 novel, with species-specific patterns and Wolbachia prevalence.

The paper identifies and characterizes Sapovirus genetic diversity in Nigerian children with Acute Flaccid Paralysis using metagenomic sequencing.

This study analyzes the microbial community shifts in HS lesions compared to healthy skin, identifying bacterial imbalances and opportunistic pathogens associated with disease progression.

The paper reports the first detection of kdr L1014F and ace-1 G119S insecticide resistance mutations in Belgian Culex mosquitoes, highlighting the need for surveillance.