Author

Umar Khalid Khan

Indian Institute of Technology KanpurORCID 0000-0003-1199-2511Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Bushra AteeqiD· 2 shared Nallasivam PalanisamyiD· 2 shared Shannon L. CarskadoniD· 2 shared Abhijit ChandraiD· 1 shared Abhimanyu Kapoor· 1 shared Akshay ShendreiD· 1 shared Anjali Tiwari· 1 shared Ayush GoeliD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCancer Biology

Bushra AteeqORCID

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2 papers

Recent·Most cited

Cancer BiologyiSciencePeer-reviewedJan 4, 2024

An integrative proteomics approach identifies tyrosine kinase KIT as a novel therapeutic target for SPINK1-positive prostate cancer.

Nishat Manzar, Umar Khalid Khan, Ayush Goel…·Bushra Ateeq

The paper identifies KIT as a therapeutic target for SPINK1-positive prostate cancer through integrative proteomics and shows KIT inhibition reduces tumor growth and metastasis.

12 citations

humanproteomics

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Cancer BiologybioRxivPreprintJul 18, 2023

Transcriptional regulation of Dyskerin via canonical WNT signaling modulates sphingolipid biosynthesis and drives colorectal cancer.

Shivansh Nigam, Umar Khalid Khan, Ayush Praveen…·Bushra Ateeq

This study identifies DKC1 as a key regulator in colorectal cancer progression through WNT signaling, showing its role in sphingolipid biosynthesis and proposing ceramides as potential biomarkers.

DOI 10.1101/2023.07.18.549480

humanbulk RNA-seq

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