Annarita Di Lorenzo

Adipocyte-specific deletion of Prdm16 ablates beige fat identity, derepresses the secreted enzyme Qsox1, and induces vascular fibrosis, angiotensin II hyperreactivity, and elevated blood pressure in mice.

This study shows that PET imaging with [68Ga]Ga-FAPI-04 detects early cardiotoxicity from anthracycline chemotherapy before echocardiography, by targeting fibroblast activation protein alpha (FAP).

This study shows that a high fat diet improves mitochondrial cardiomyopathy in CHCHD10 mutant mice by enhancing fatty acid utilization and reducing protein aggregation.