Mahavir Singh

This study identifies hnRNPA1 as a host factor that binds and remodels SARS-CoV-2 genomic G-quadruplexes through its UP1 domain, suggesting a mechanism for viral replication.

This study characterizes the C-terminal domain of SARS-CoV-2 nucleocapsid protein binding to TRS RNA with high affinity and forming higher-order assemblies through experimental assays.

This study investigates the interaction between SARS-CoV-2 N protein and hnRNPA1, showing their physical binding and phase separation, and highlights hnRNPA1's role in suppressing viral replication.

This study investigates the role of intracellular and extracellular formate in regulating virulence genes in Salmonella Typhimurium, showing that pflB deletion affects flagellation and virulence gene expression through pH and membrane changes.

This study identifies SIRT2 as a regulator of global protein synthesis by modulating Rheb-GTPase activity, showing its potential as a therapeutic target for diseases with increased protein synthesis.

This study shows that c-di-AMP modulates antibiotic sensitivity in M. smegmatis by interacting with protein effectors or mRNA 5-UTR regions, leading to differential drug resistance.