Author
Ollscoil na Gaillimhe – University of GalwayORCID 0000-0003-1337-5656Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Stefanus Bernard, Michael D. Rainey, Corrado Santocanale, Colm J. Ryan
The paper develops GuideRefine to identify and remove multi-targeting and off-targeting sgRNAs from CRISPR-KO libraries, improving the accuracy of gene hit lists.
Michael D. Rainey, Stefanus Bernard, Aikaterini Pravi…·Corrado Santocanale
The paper identifies CDK8 as a third kinase involved in DNA replication origin activation by showing its cooperation with CDC7 and its role in phosphorylating MCM4.
Anja Göder, Chrystelle Antoinat Maric, Michael D. Rainey…·Corrado Santocanale
This study shows DBF4, not DRF1, is essential for CDC7 kinase function at replication forks, while both subunits support bulk DNA replication.