Kristina Haslinger

This study enables the de novo biosynthesis of alpinetin in E. coli through directed evolution of a 5-O-methyltransferase, demonstrating its broad substrate specificity for O-methylated flavonoids.

This paper characterizes two fungal polyketide synthases that produce substituted 2-quinolones and (thio)coumarins, demonstrating their potential for biocatalytic drug discovery.

The paper presents a de novo whole genome assembly of the green shore crab using long-read sequencing and provides a DNA extraction protocol for brachyuran crabs.

The paper integrates genomics and metabolomics to identify anti-MRSA natural products from the endophytic fungus Neocucurbitaria sp. VM-36, discovering a phomasetin analog with potent bactericidal activity against S. aureus.

This study characterizes fungal type III polyketide synthases (T3PKSs) by analyzing their genomic context and substrate specificity, and develops a machine learning model to predict their substrate preferences.

The paper identifies and partially reconstitutes the biosynthetic pathway of hericenones in Hericium erinaceus using heterologous expression in Aspergillus oryzae.

The paper develops a host-exclusive primer design workflow for long-read metabarcoding, enabling efficient amplification of fungal rDNA from mixed DNA samples.

The paper identifies and expresses two functional 4-O-dimethylallyl-L-tyrosine synthases from lichen-forming fungi, revealing their substrate specificity and potential for biocatalytic applications.

This study sequenced the genome of Anthostomella pinea and analyzed its secondary metabolites, revealing 91 biosynthetic gene clusters and the antibiotic xanthoepocin.

This study produces naringenin in Penicillium rubens using genetic engineering and identifies a novel degradation pathway for this compound.

This study identifies multiple siderophores produced by Serratia plymuthica V4 using three gene clusters and a polyamine superpathway, highlighting enterobactin's role in bacterial fitness and the strain's potential for industrial polyamine production.