Jennifer Tisoncik-Go

This study links reduced short-chain fatty acid levels with elevated inflammation in Zika-virus infected macaques, suggesting microbial dysfunction contributes to CNS and systemic inflammation.

This study investigates ZIKV infection in fetal brain tissue, identifying astrocyte immune responses and neuronal dysfunction linked to congenital Zika syndrome.

This study investigates how SIV-induced immunosuppression affects ZIKV replication and persistence in pigtail macaques, finding increased viral persistence and chronic immune activation in the gastrointestinal tract.

The paper identifies a gut microbial signature predictive of RhCMV/SIV vaccine efficacy in rhesus macaques using 16S rRNA analysis and compositional data techniques.

This study investigates the effects of prenatal Zika virus exposure on fetal myelin structure and oligodendrocyte maturation in pigtail macaques, finding disruptions in myelin formation and gene expression related to oligodendrocyte development.

scPathoQuant efficiently aligns and quantifies pathogen and host reads from scRNA-seq data in a single step, enabling analysis of viral and host sequence abundance in infected cells.