Elena Rainero

This study shows that nutrient stress increases α2 integrin expression via RAS/MAPK and mTOR pathways, enhancing cancer cell motility and correlating with poor pancreatic cancer prognosis.

This study shows collagen I supports cancer cell survival by activating mTORC1 and enhancing amino acid import through LAT1-4F2hc, which is linked to poor prognosis in breast and pancreatic cancers.

This study shows ADAMTS5 promotes ovarian cancer cell invasion via Rab25 and NF-κB signaling, with high ADAMTS5 expression linked to poor patient prognosis.

This study identifies 2β1 integrin and MAP3K1/p38 signaling as regulators of ECM internalization, which promotes cancer cell migration and invasion in breast and pancreatic cancers.