Hans‐Helge Seifert

This study establishes a patient-derived organoid-xenograft platform that models prostate cancer progression, identifies biomarkers, and predicts treatment response.

This study develops an ECM-free culture system for prostate cancer organoids, revealing diverse tumor lineages and identifying in vitro-enriched cell types through single-cell RNA sequencing.

The paper investigates mechanical instability in bladder epithelium at cancer onset, showing stiffness changes and morphological features similar to early tumors.