Lukas Bubendorf

The paper identifies MTAP deficiency as a biomarker in lung neuroendocrine neoplasms, distinguishing carcinoids from SCLC and LCNEC, and shows it is not caused by 9p21 deletion or promoter hypermethylation.

This study establishes a patient-derived organoid-xenograft platform that models prostate cancer progression, identifies biomarkers, and predicts treatment response.

This study develops an ECM-free culture system for prostate cancer organoids, revealing diverse tumor lineages and identifying in vitro-enriched cell types through single-cell RNA sequencing.

This study identifies TRIM24 as a target for preventing prostate cancer progression by degrading it to counteract AR inhibition adaptation and tumor relapse.

The paper investigates mechanical instability in bladder epithelium at cancer onset, showing stiffness changes and morphological features similar to early tumors.