Wencheng Ji

The paper shows that bacterial RNA polymerase's C-terminal domains accelerate DNA binding through a physical mechanism involving flexible tethers.

This study identifies design principles of transcription factor intrinsically disordered regions that enhance binding affinity and search time for target DNA.

The paper uses optogenetic tools to control pheromone gradients in budding yeast, enabling spatial regulation of mating behavior and cell fusion.

The paper identifies a self-extinguishing relay wave mechanism in human neutrophils that controls swarming and recruitment levels through an NADPH-oxidase-based feedback loop.