Janez Plavec

The paper identifies SERF2 as a protein involved in stress granule formation and characterizes its interactions with G-quadruplex RNA structures to study liquid-liquid phase transitions.

This study uses fast MAS NMR to identify G-quartet and double-stranded structures in GGGGCC RNA aggregates linked to ALS and FTD.

The paper investigates the lipid phase behavior in thylakoid membrane curvature regions of spinach, revealing an isotropic non-bilayer phase enriched in monogalactosyldiacylglycerol.

The paper investigates the selectivity of the iMab antibody for i-motif structures, showing it binds both intramolecular and intermolecular iMs, and highlights the impact of experimental conditions on binding.

The paper identifies over 650,000 i-motif structures in human genomic DNA using immunoprecipitation and sequencing, showing their widespread distribution and association with highly expressed genes and G0/G1 phase upregulated genes.

This study shows Znf706 promotes protein aggregation but binds G-quadruplexes, which suppresses aggregation and affects mRNA levels.

The paper identifies CPI-169 as a competitive inhibitor of SARS-CoV-2 PLpro that targets the same binding site as GRL-0617, through a drug repurposing screening approach that accounts for redox-sensitivity.