Author

Berke Türkaydin

Leibniz-Forschungsinstitut für Molekulare PharmakologieORCID 0000-0003-1699-0312Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:protein folding & dynamics· 2 Approach:biophysical modeling· 1 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1 Approach:mechanistic / dynamical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Marcus ScheweiD· 2 shared Thomas BaukrowitziD· 2 shared Chaimae BenkerdaghiD· 1 shared Elena B. RieliD· 1 shared Francesco Luigi GervasioiD· 1 shared Friederike SchulziD· 1 shared Han SuniD· 1 shared Han SuniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBiophysics

Marcus ScheweORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintFeb 14, 2026

Energetic cross-talk of filter gate and lower helices drives polymodal regulation and disease in TREK K2P channels

Berke Türkaydin, Valerio Rizzi, Chaimae Benkerdagh…·Han Sun

This study uses molecular dynamics to analyze TREK-2 channel conformational changes, linking them to disease mechanisms and drug discovery.

DOI 10.64898/2026.02.13.705734

electrophysiologymechanistic / dynamical model

𝕏 PostBluesky

BiophysicsNature CommunicationsPeer-reviewedMay 31, 2024

From head to tail - Atomistic mechanism of long-range coupling from the cytosolic sensor domain to the selectivity filter in TREK K2P channels

Berke Türkaydin, Marcus Schewe, Elena B. Riel…·Han Sun

The paper reveals the atomistic mechanism of long-range coupling between the cytosolic sensor domain and the selectivity filter in TREK K2P channels, showing how conformational changes and phosphorylation regulate channel activity.

24 citations

structural biologybiophysical modeling

𝕏 PostBluesky