Filippo Rusconi

This study identifies mitochondrial calcium flux as a critical regulator of oligodendrocyte regeneration, showing its role in proliferation, differentiation, and lesion site repopulation.

The paper identifies OutB, an inner membrane protein in Dickeya dadantii, as covalently attached to peptidoglycan, similar to Braun lipoprotein, and shows that Ldt03 and Ldt84 enzymes mediate this attachment through amide bond formation.

The paper uses mass spectrometry to study the kinetics of Braun lipoprotein (Lpp) tethering to peptidoglycan (PG) and its hydrolysis, revealing dynamic equilibrium between PG-tethered and free Lpp forms.

The paper introduces an automated workflow and software tools for analyzing oligodendroglial calcium signals in mouse myelin repair models, revealing uncorrelated spontaneous Ca2+ activity in demyelinated lesions.