Dual Modes of Gene Regulation by CDK12
Yubao Wang, Apoorva Baluapuri, Cherubin Manokaran…·Thomas M. Roberts
This study shows CDK12 inhibition both downregulates and upregulates gene expression, with implications for cancer therapy.
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Harvard UniversityORCID 0000-0003-1908-2926Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Yubao Wang, Apoorva Baluapuri, Cherubin Manokaran…·Thomas M. Roberts
This study shows CDK12 inhibition both downregulates and upregulates gene expression, with implications for cancer therapy.
Tao Jiang, Alison A. Motsinger‐Reif
This paper introduces a machine learning method to detect same-species contamination in sequencing data using variant calling information, achieving high sensitivity and specificity in both simulated and real data.
Pan Li, Yifan Wei, Miao Mei…·Qiangfeng Cliff Zhang
This study identifies RNA structural elements in ZIKV strains that influence infectivity through comparative in vivo analysis.