Nathan D. Grubaugh

This study tracks DENV lineage dynamics over two decades using 37,828 genomes, revealing regional diversity patterns and the impact of COVID-19 on lineage persistence and spread.

This study uses phylogeographic and phylodynamic methods to analyze DENV genome data, revealing asymmetric global spread patterns and the role of travel over climate in DENV transmission.

This study uses whole-genome sequencing and phylodynamic methods to analyze the evolutionary history and ecological dynamics of Jamestown Canyon virus, revealing its slow evolution and transmission patterns.

The paper develops MSSPE, a method to enrich low-abundance viruses in wastewater using spiked primers, improving detection in resource-limited settings.

This study evaluates the inhibition of genetically diverse dengue virus strains by two Wolbachia strains, finding differential effectiveness and implications for control strategies.

This study examines how successive blood feeding affects DENV-2 dissemination and survival in Ae. aegypti mosquitoes with and without Wolbachia, finding that Wolbachia strongly inhibits virus transmission despite frequent feeding.

This study analyzes the genomic data of SARS-CoV-2 Omicron BA.5 variants in the U.S. to understand their emergence patterns and transmission dynamics.

This study analyzes DENV-3 genomes in Brazil to identify multiple introductions of the 3III_B.3.2 lineage and trace its spread from the Caribbean and Costa Rica.

This paper develops tiled amplicon sequencing panels for whole-genome sequencing of pathogenic bacteria without culturing, enabling drug resistance classification from clinical samples.

The study surveys white-footed mice in Connecticut, finding low SARS-CoV-2 seroprevalence and identifying two divergent betacoronaviruses.

This study reconstructs the emergence and spread of Powassan virus lineage II in the northeastern U.S. using genomic data, finding a south-to-north dispersal pattern and population growth.

This paper describes a method to sequence Zika and other virus genomes directly from clinical samples using multiplex PCR and portable sequencing technologies, achieving complete genomes in 1-2 days.

This study sequenced 110 Zika virus genomes from 10 countries, revealing rapid expansion in Brazil, multiple introductions into other regions, and undetected circulation before confirmed cases.

The paper uses ZIKV genomes to estimate the origin and spread of Zika virus in Brazil and the Americas, providing a timeframe for baseline microcephaly rates.