Gordon C. S. Smith

This study tracks maternal immune gene expression and genetic regulation throughout pregnancy, revealing dynamic changes and genetic interactions linked to pregnancy complications.

This study profiles the pregnancy plasma proteome using a novel precipitation method, identifying 433 protein groups with tissue-specific associations and changes during gestation.

The paper identifies 762 transcripts uniquely depleted in the placenta compared to 46 other human organs, highlighting mitochondrial and polyamine metabolism enrichment.

This study uses whole genome sequencing of placental biopsies to show that human placentas exhibit clonal expansions, copy number changes, and developmental bottlenecks similar to childhood cancer.