Author

Anderson R. Frank

The University of Texas Southwestern Medical CenterORCID 0000-0003-2239-9975Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

David G. McFaddeniD· 2 shared Abby C Jurasin· 1 shared Celia de la Calle ArreguiiD· 1 shared Cheryl M. LewisiD· 1 shared Florentina VandiveriD· 1 shared Jiwoong KimiD· 1 shared Justin A. Bishop· 1 shared Kelvin MuniD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersCancer Biology

David G. McFaddenORCID

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3 papers

Recent·Most cited

Cancer BiologyScience AdvancesPeer-reviewedJul 3, 2026

Loss of heterozygosity exposes germline mutations in complex I and drives Warburg metabolism in oncocytic carcinoma of the thyroid

Celia de la Calle Arregui, Anderson R. Frank, Kelvin Mun…·David G. McFadden

The paper identifies germline mutations in complex I subunits as a driver of Warburg metabolism in oncocytic thyroid carcinoma through loss of heterozygosity.

DOI 10.1126/sciadv.aee5417

humanwhole-genome sequencing

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Cell BiologybioRxivPreprintApr 3, 2026

Proteomics reveals extensive phosphoregulation of outer kinetochore protein KNL1

Abby C Jurasin, Anderson R. Frank, Sue Biggins

The paper identifies 111 phosphorylation sites on KNL1, showing extensive phosphoregulation in response to microtubule-disrupting compounds.

DOI 10.64898/2026.03.13.711714

humanproteomics

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Cancer BiologyACS Chemical BiologyPeer-reviewedJan 25, 2024

Forward genetic screens identify mechanisms of resistance to small molecule lactate dehydrogenase inhibitors

Anderson R. Frank, Florentina Vandiver, David G. McFadden

This study identifies two resistance mechanisms to LDH inhibitors in complex I-mutant HTC models through forward genetic screens.

2 citations

humanbulk RNA-seq

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