Nicolai Bache

This paper presents a method combining DIA MS/MS and MS1-only spectra for rapid UTI pathogen identification, achieving high accuracy in both controlled and clinical samples.

The paper introduces SPEC, a proteomics sample preparation method that improves proteome depth and reproducibility from limited samples.

This study improves single-cell proteomics by increasing protein identification from ~2000 to over 5000 per cell and enhancing throughput and reliability.

The paper presents an automated workflow for proteome and phosphoproteome sample preparation, enabling high-throughput clinical proteomics analysis of metastatic melanoma patients' plasma.

One-Tip provides a proteomics method for high-depth protein identification from minimal cell samples and single zygotes with high throughput.

The paper develops a high-sensitivity mass spectrometry workflow to quantify single-cell proteome changes upon perturbation, revealing a stable core proteome despite transcriptomic variability.

The paper demonstrates that Evosep One technology enables faster quantitative proteome analysis with comparable coverage to conventional methods.

The paper introduces the timsTOF Pro instrument with online PASEF, achieving high sensitivity and reproducibility in proteomics.