Author

Joan Sebastián Gallego‐Murillo

Amsterdam UMC Location University of AmsterdamORCID 0000-0003-2381-2012Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

Angelo D'AlessandroiD· 2 shared Emile van den AkkeriD· 2 shared Julie A. ReisziD· 2 shared Marieke v. LinderniD· 2 shared Nurcan YağcıiD· 2 shared A. WahliD· 1 shared Amy ArgabrightiD· 1 shared Arthur Flohr SvendseniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersCell Biology

Angelo D'AlessandroORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintJun 2, 2026

Metabolic profiling of cultured erythroblast for the production of transfusion-ready cultured red blood cells

Joan Sebastián Gallego‐Murillo, Ingeborg van Lakwijk, Nurcan Yağcı…·Emile van den Akker

This study identifies metabolic stress in high-density erythroblast cultures, showing that small molecular weight metabolites limit proliferation and suggesting strategies to improve cell productivity.

DOI 10.64898/2026.06.02.729469

humanmetabolomics

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Cell BiologyScientific ReportsPeer-reviewedDec 4, 2024

Differentiating erythroblasts adapt to turbulent flow by accelerating maturation and activating cholesterol biosynthesis.

Giulia Iacono, Asena Abay, Joan Sebastián Gallego‐Murillo…·Emile van den Akker

This study shows that erythroblasts adapt to shear stress by accelerating maturation and upregulating cholesterol biosynthesis, enhancing osmotic resistance and enucleation.

11 citations

humanbulk RNA-seq

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