Alaleh Shafiei

This study identifies the N-terminal order-disorder transition as critical for IscU's metamorphic behavior and shows it can be modulated by a peptide mimic.

This study uses 4D crystallography to capture transient dynamics of IF1 binding to the 30S ribosomal subunit, revealing allostery and interactions during translation initiation.

This study determines the structure of the 50S ribosomal subunit from Thermus thermophilus at ambient temperature using serial femtosecond X-ray crystallography, revealing new dynamics and antibiotic binding sites.