Medhanjali Dasgupta

The paper presents a high-resolution X-ray structure of a Gln143Asn MnSOD variant, revealing multiple H2O2 binding sites beyond the canonical LIG and PEO positions.

The paper determines the structure of active Ni(I)-Methyl-CoM reductase, revealing how it catalyzes methane formation and providing insights for methane emission control and biofuel production.

This study investigates the role of Tyr34 in MnSOD catalysis using neutron diffraction, X-ray spectroscopy, and quantum chemistry calculations, revealing its impact on proton-coupled electron transfer.

The paper uses XFEL crystallography to observe conformational changes in an enzyme during catalysis, revealing ionization-linked dynamics that control catalytic activity.