Françis Rodier

This study identifies combination therapies for melanoma that enhance senolytic sensitivity by analyzing senescence responses to different treatments.

This study shows that senescence in ovarian cancer cells after chemotherapy correlates with better patient survival, suggesting senescence could be a therapeutic target.

This study shows that high 53BP1 levels in ovarian cancer are linked to poor survival and chemotherapy resistance, suggesting it could be a therapeutic target.

This study shows that telomere uncapping does not directly trigger senescence but leads to genomic instability through telomere fusions and DNA breaks, resulting in irreversible damage.