Francesco Padovani

The paper uses single-cell imaging and machine learning to show Bck2 is critical for yeast cell size adaptation to nutrient changes, unlike in steady-state conditions.

SpotMAX is an AI-driven framework for automated spot detection and quantification in microscopy data, outperforming existing tools and human annotators across diverse biological applications.

Disruption of KEA-mediated chloroplast ion homeostasis in Chlamydomonas reinhardtii reveals conserved and lineage-specific control of plastid rRNA processing and cell cycle progression.

This study shows that yeast cells adapt to changes in mitochondrial DNA copy number through retrograde signaling and protein dosage compensation, allowing robust growth despite mtDNA fluctuations.

This study shows that yeast cells use local mitochondrial physiology to select for functional mtDNA, with purifying selection against specific mtDNA mutations under fermentative conditions.

This study investigates how septin ring size scales with cell size in budding yeast by combining computational modeling, live-cell imaging, and genetic experiments.

This study shows that impaired mitochondrial fusion in yeast leads to mtDNA loss due to unequal distribution and reduced synthesis.

This study compares spheroid formation and behavior across six ultra-low attachment plate types using four human cell lines, finding size and eccentricity differences that suggest plate type impacts experimental outcomes.

The paper introduces a genetic fluorescent reporter, mt-HI-NESS, to visualize mitochondrial nucleoids in live cells without affecting mtDNA replication or expression.