Author

Francesco Pontiggia

Howard Hughes Medical InstituteORCID 0000-0003-2569-6238Unclaimed ORCID profile · follow to get notified of new preprints

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Biophysics· 1

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Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

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Dorothee KerniD· 1 shared Gabriel Ernesto JaraiD· 1 shared Marcelo Adrian MartiiD· 1 shared Renee OtteniD· 1 shared Roman V. AgafonoviD· 1 shared

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2023-2023 · peak 1/yr

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1 shared paperBiophysics

Dorothee KernORCID

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1 paper

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BiophysicsbioRxivOct 3, 2023

Wide Transition-State Ensemble as Key Component for Enzyme Catalysis

Gabriel Ernesto Jara, Francesco Pontiggia, Renee Otten…·Dorothee Kern

The paper investigates the transition-state ensemble in adenylate kinase, finding a broad set of energetically equivalent configurations that support efficient enzyme catalysis.

14 citations

statistical modelprotein folding & dynamics

𝕏 PostBluesky